Advances in Computational Biology: Proceedings of the 2nd - download pdf or read online

By Ivan Mura (auth.), Luis F. Castillo, Marco Cristancho, Gustavo Isaza, Andrés Pinzón, Juan Manuel Corchado Rodríguez (eds.)

ISBN-10: 3319015672

ISBN-13: 9783319015675

ISBN-10: 3319015680

ISBN-13: 9783319015682

This quantity compiles permitted contributions for the 2d version of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous assessment strategy during which fifty four papers have been approved for book from 119 submitted contributions. Bioinformatics and Computational Biology are parts of data that experience emerged as a result of advances that experience taken position within the organic Sciences and its integration with info Sciences. the growth of initiatives concerning the examine of genomes has led the way in which within the creation of significant quantities of series info which should be equipped, analyzed and saved to appreciate phenomena linked to residing organisms on the topic of their evolution, habit in several ecosystems, and the advance of functions that may be derived from this analysis.

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Additional resources for Advances in Computational Biology: Proceedings of the 2nd Colombian Congress on Computational Biology and Bioinformatics (CCBCOL)

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Castillo et al. 1007/978-3-319-01568-2_5, © Springer International Publishing Switzerland 2014 29 30 R. Cabezas et al. phosphatidylinositol 3-kinase (PI-3K)/Akt, the PLCγ and the JAK-STAT pathways [7]. g. E- cadherin and integrins) and G-protein-coupled receptors (GPCR). Furthermore, it has been noticed that the EGFR is able to interact with other receptors and perform transactivavion signaling by virtue of the fact that it does not require binding of its ligand for tyrosine kinase activity and dimerization [8,9].

Each homodimer (WT and M6) was placed in a cubic box with explicit TIP3P water to which 100 mM NaCl was added, including neutralizing counterions. Following steepest descents minimization, each of the homodimer systems was equilibrated in two steps, with position restraints applied to peptide heavy atoms throughout. The first phase involved simulating for 50 ps under a constant volume (NVT) ensemble. Protein and nonprotein atoms were coupled to separate temperature coupling baths, and temperature was maintained at 310 K using the Berendsen weak coupling method.

J. Biol. Chem. 266, 2746–2752 (1991) 17. : Translocation of pp60csrc from the plasma membrane to the cytosol after stimulation by platelet derived growth factor. J. Biol. Chem. 268, 19552–19558 (1993) 18. : Crystal structure of human platelet-derived growth factor BB. EMBO J. (11), 3921–3926 (1992) 19. : The Protein Data Bank and the challenge of structural genomics. Nature Structural Biology (11), 957–959 (2000) 20. : ClusPro: an automated docking and discrimination method for the prediction of protein complexes.

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Advances in Computational Biology: Proceedings of the 2nd Colombian Congress on Computational Biology and Bioinformatics (CCBCOL) by Ivan Mura (auth.), Luis F. Castillo, Marco Cristancho, Gustavo Isaza, Andrés Pinzón, Juan Manuel Corchado Rodríguez (eds.)


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