Arenaviruses I: The Epidemiology, Molecular and Cell Biology by J. C. S. Clegg (auth.), Professor Dr. Michael B. A. Oldstone PDF

By J. C. S. Clegg (auth.), Professor Dr. Michael B. A. Oldstone (eds.)

ISBN-10: 3540422447

ISBN-13: 9783540422440

ISBN-10: 3642560296

ISBN-13: 9783642560293

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Additional resources for Arenaviruses I: The Epidemiology, Molecular and Cell Biology of Arenaviruses

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1999; FURANO et al. 1994; HANNI et al. 1995; HucHoN et al. 1999; USDIN et al. 1995) has suggested that Mastomys, along with most African murids, may belong in a unique African subfamily of rodents allied to Murinae (see also GRAUR 1994). Mastomys, described as a genus in 1915 by Oldfield Thomas, is currently thought to be constituted by eight species (MUSSER and CARLETON 1993): M. angolensis (Angola and southern Zaire), M. coucha (South Africa, southern and western Zimbabwe, and central Namibia), M.

Within this latter lineage, Guinean and Liberian strains appeared more basal than those from Sierra Leone. Both these findings are consistent with the notion of an ancestral virus population in Nigeria, which has moved westwards to occupy the endemic areas of Liberia, Guinea, and Sierra Leone. This might have happened by spread of the virus through the rodent population, or by movement of the viruscarrying rodents themselves. The situation in the intervening territory between Nigeria and Liberia remains unclear, although, as noted above, there is evidence of the presence of the virus (GONrnER et al.

However, VIEGAS-PEQUIGNOT et aI. (1983) and BASKEVICH and ORLOV (1993) reported on additional cytotypes, all 2n = 32 but with radically differing fundamental numbers, which could not be considered conspecific with M. huberti. Thus, there exist (at least) four distinct 2n = 32 cytotypes within M. huberti, no combinations of which should give rise to fertile F 1 hybrids given the nature of the chromosomal rearrangements between each possible pair. By the classical definition of species, failure to interbreed is prima facie evidence of non-conspecificity.

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Arenaviruses I: The Epidemiology, Molecular and Cell Biology of Arenaviruses by J. C. S. Clegg (auth.), Professor Dr. Michael B. A. Oldstone (eds.)


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